By Sheldon J. Park,Jennifer R. Cochran
Experimental protein engineering and computational protein layout are extensive yet complementary ideas for constructing proteins with altered or novel structural houses and organic services. by means of describing state-of-the-art advances in either one of those fields, Protein Engineering and Design goals to domesticate a synergistic method of protein science.
Experimental Protein Engineering
The first 1/2 the booklet discusses experimental techniques to protein engineering and begins by way of describing a number of high-throughput screening structures for protein engineering. Key recommendations used for range new release also are mentioned. the following few chapters current examples of therapeutics, enzymes, biomaterials, and different proteins which have been engineered through rational or combinatorial ways. The part finishes with a bankruptcy at the use of non-natural amino acids in protein engineering.
Computational Protein Design
The moment half the ebook introduces computational protein layout, starting with a bankruptcy on computational and informatics algorithms utilized in protein engineering. middle elements of computational protein layout are then mentioned intimately, and examples of heuristic protein layout are supplied. next chapters current examples of ways computational layout has performed a serious function in advancing the sphere of protein engineering. Concluding with a bankruptcy outlining present demanding situations within the box, this e-book makes computational protein layout and diversity-oriented protein engineering broadly available to a extensive viewers in academia and alike.
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Protein Engineering and Design by Sheldon J. Park,Jennifer R. Cochran